Soft Tissue Evaluation of an Immediate Esthetic Zone Single Implant with a Stereolithographic Guide Using 3D Reconstruction and a CAD/CAM Customized Titanium Anatomic Abutment

The Eyelash Curlers replacement of an unrestorable tooth with a single implant-supported prosthesis is a treatment with predictable and successful outcomes.The anterior maxilla region is a complicated site for such treatment, due to its esthetic, functional, and physiological sensitivity.The purpose of this study was to evaluate the changes in the

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Local-Global Graph Fusion to Enhance scRNA-Seq Clustering

Single-cell RNA sequencing (scRNA-seq) is crucial for demystifying the cell heterogeneity and differentiation processes, enabling the identification of distinct cell subtypes within a population.However, most of the existing approaches are feeble to comprehensively investigate the interactive relationships between cells and exploit the topological

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Evaluation of Transdermal Transport and Concurrent Cutaneous Hydrolysis of Timolol Prodrug for the Treatment of Infantile Hemangiomas

Infantile Intenze individual hemangiomas (IH) leave sequelae after involution.Topical application of timolol maleate (TM) is the mainstream treatment for superficial lesions but is limited by its low penetrable properties.We aimed to develop a superior skin permeation drug while maintaining the therapeutic properties of timolol.We predict that this

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